Calibrant's proteomic services

Calibrant offers a wide array of custom proteomic services designed to provide the highest data quality for your critical specimens. We have extensive experience working with pharmaceutical and biotechnology companies, government agencies, and academic researchers, ranging from our standardized proteomic analysis options to the development of custom workflows designed to maximize the information content and quality for challenging samples.

We offer a full range of services, including:

• Targeted analysis of microdissected tissue specimens using the Gemini™ discovery engine
• FFPE archival tissue protein profiling
• Analysis of protein complexes for protein–protein interactions
• PTM analysis including phosphorylation and glycocylation
• Characterization of protein product and protein contaminants
• Drug mechanism of action & predictive toxicology
• Antibody characterization – intact mass determination of heavy and light chain, peptide mapping of heavy and light chain
• Absolute protein quantification using stable isotopes and Multiple Reaction Monitoring (MRM) of specific peptides from proteins of interest

Targeted proteomics and the Gemini™ engine

Calibrant’s proprietary Gemini™ discovery engine enables comprehensive and quantitative protein profiling of isolated and homogeneous cell populations from both fresh and archival formalin-fixed tissues, allowing our customers to approach the full biology of disease pathogenesis with exquisite sensitivity. With sample requirements uniquely matched to microdissection methods including laser capture microdissection (LCM), and coupled with an integrated bioinformatics suite enabling effective data mining within a biological context, Calibrant's technologies provides real-world benefits for drug discovery, drug development, and the identification of predictive markers for personalized medicine.

Get more information:

• Targeted proteomics using Gemini™ >
• Proteomic services >